Moviehole recently talked to Seth Rogen about his past, current, and future projects and the actor let this much slip about sequels:
Rogen says they’re definitely considering a sequel. “They’re been wanting us to do a sequel to Superbad for so long – but we’ve held off. We eventually said No. But this one, it’s not a precious coming-of-age story like Superbad, it’s a weed action-movie and if it did well, and they gave us like $50 million dollars (as opposed to the $26M we got for this one) we could benefit from that.”